منابع مشابه
Peptide antibiotics.
The era of the "classical antibiotic" may be over. The emergence of resistance has seen to that. Yet no truly novel class of antibacterial agent has come on the market in the past 30 years. Currently there is great interest in peptide antibiotics, especially the cationic peptides. Thousands of such molecules have been synthesised and just a few are entering clinical trials. Because they kill ba...
متن کاملNew generation of peptide antibiotics.
The increasing antibiotic resistance of pathogenic bacteria calls for the development of alternative antimicrobial strategies. Possible approaches include the development of novel, broad-spectrum antibiotics as well as specific targeting of individual bacterial virulence factors. It is impossible to decide currently which strategy will prove more successful in the future since they both promise...
متن کاملAntimicrobial preservative effectiveness of natural peptide antibiotics.
The constantly growing resistance of microbes to drugs and other substances which fight microbial infections leads to search for new antimicrobial substances. Among substances which attract the scientists attention are antimicrobial peptides. Such compounds are quite common in nature and belong to the most important elements of the innate immune system of all living organisms. Numerous antimicr...
متن کاملBiochemistry of Some Peptide and Steroid Antibiotics
and the level of ATP in platelets. The possibility exists that ATP may represent one of the anchoring sites for 5-HT in the body. At present, it seems most appropriate to look upon 5-HT in platelets as a transportation form of the amine, since in this locus, unlike most of the other sites in which 5-HT is found in high concentration, enzymes concerned with the formation of the amine are not pre...
متن کاملDefensins. Natural peptide antibiotics of human neutrophils.
We extracted a granule-rich sediment from normal human neutrophils and subjected it to chromatographic, electrophoretic, and functional analysis. The extract contained three small (molecular weight less than 3,500) antibiotic peptides that were named human neutrophil peptide (HNP)-1, HNP-2, and HNP-3, and which will be referred to as "defensins." HNP 1-3, a mixture of the three defensins, kille...
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ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 1971
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.29.1032